Oct 15, 2018 - Because milk thistle is believed to protect and regenerate the liver, it’s indicated for a variety of conditions as an alternative treatment. Certain herbal supplements, such as St. John's wort , may decrease blood levels of some statin drugs, and when taken with atorvastatin, may actually result in increased cholesterol levels. Meaning taking Milk Thistle will inhibit the metabolizing of Prednisone building up a dangerous toxicity of it in your bloodstream. Well, enzymes in the liver break down many of the substances that we eat and drink, including medications. Milk thistle might not be safe for everybody. While statins can be beneficial in lowering cholesterol and decreasing your risk for heart disease, you can see that there are many precautions to be considered. Milk thistle might decrease how quickly the liver breaks down some medications. If you are currently being treated with any of the following medications, you should not use milk thistle without first talking to your healthcare provider. The amount of vitamin D used in this study was very large (up to 50,000 IU twice a week) and potentially toxic. According to Dr. Stuart and the 2005 International Journal of Oncology, milk thistle contains sylimarin, which is a combination of three phenolic compounds that have antioxidant and anti-inflammatory effects 2. There’s no hard a fast rule. What does this have to do with HIV? These are only a few of the possible drug interactions, which is why it is very important that you discuss your medical history and all medications—prescription or otherwise—with your healthcare team before taking a statin. Before taking milk thistle, talk to your doctor, pharmacist, or health care professional if you have allergies (especially to plants), have any medical conditions, or if you take other medicines or other herbal/health supplements. People taking statins usually start with the dose recommended for their health issues. 6 posts • Page 1 of 1. In a preliminary trial, supplementation with vitamin D appeared to prevent muscle-related side effects in patients taking statin drugs. I know we are curious for natural/herbal remedies but please run them by your doctor first!! Milk Thistle, Red Rice Yeast, CoQ10, Liver function. you might ask. This article will take you through the evidence behind milk thistle’s purported benefits and uses. Prednisone!! Don't take milk thistle if you're allergic to it, pregnant, or hormone-sensitive. Milk thistle is a wonderful herb which can benefit many people with thyroid and autoimmune thyroid conditions. This is because statins can affect your liver, and this is more likely to cause serious problems if you already have a severely damaged liver. Milk thistle seeds only take only around two weeks to germinate. There are no interactions between milk thistle and alcohol. Before starting to take statins, you should have a blood test to ensure your liver is in a relatively good condition. Ibuprofen can reduce the effect of Losartan and may get your blood pressure high. That means you can take it after drinking alcohol. You are trying to load Blausen Medical's Human Atlas. Can you take Ramipril and Milk thistle? Solubility is increased when combined with phosphatidylcholine. Most likely your drugs were not studied in clinical trials based on patients like you. You can take milk thistle in capsule or tablet form 2. Milk Thistle Drug Interactions Statins Results Test Function Explained Pkpi System. Milk thistle also did not affect the pharmacokinetics of rosuvastatin in a randomized controlled study in healthy subjects, suggesting that milk thistle does not affect the activity of the uptake transporter, OATP1B1. This is an amino-acid like compound which neutralizes toxins. 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